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Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation

BACKGROUND: CTCF is a well-established chromatin architectural protein that also plays various roles in transcriptional regulation. While CTCF biology has been extensively studied, how the domains of CTCF function to regulate transcription remains unknown. Additionally, the original auxin-inducible...

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Detalles Bibliográficos
Autores principales: Hyle, Judith, Djekidel, Mohamed Nadhir, Williams, Justin, Wright, Shaela, Shao, Ying, Xu, Beisi, Li, Chunliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878928/
https://www.ncbi.nlm.nih.gov/pubmed/36698211
http://dx.doi.org/10.1186/s13059-022-02843-3