Targeting Orexin Receptors for the Treatment of Insomnia: From Physiological Mechanisms to Current Clinical Evidence and Recommendations

After a detailed description of orexins and their roles in sleep and other medical disorders, we discuss here the current clinical evidence on the effects of dual (DORAs) or selective (SORAs) orexin receptor antagonists on insomnia with the aim to provide recommendations for their further assessment...

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Detalles Bibliográficos
Autores principales: Mogavero, Maria P, Silvani, Alessandro, Lanza, Giuseppe, DelRosso, Lourdes M, Ferini-Strambi, Luigi, Ferri, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879039/
https://www.ncbi.nlm.nih.gov/pubmed/36713640
http://dx.doi.org/10.2147/NSS.S201994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879039/
https://www.ncbi.nlm.nih.gov/pubmed/36713640
http://dx.doi.org/10.2147/NSS.S201994

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