Cargando…

ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats

Oxidative stress and neuroapoptosis are key pathological processes after subarachnoid hemorrhage (SAH). The present study evaluated the anti-oxidation and anti-apoptotic neuroprotective effects of the apoptosis signal-regulating kinase 1 (ASK1) inhibitor ethyl-2,7-dioxo-2,7-dihydro-3H-naphtho(1,2,3-...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Jiajia, Yuan, Wen, Jiang, Juan, Wang, Jikai, Yan, Xiaoxin, Liu, Fei, Liu, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879074/
https://www.ncbi.nlm.nih.gov/pubmed/36633130
http://dx.doi.org/10.3892/mmr.2023.12934