Comparison of pharmacokinetics and bioavailability of bedaquiline fumarate, benzoate and maleate in dogs

BACKGROUND: Bedaquiline (BDQ) as a fumarate salt is indicated as part of a regimen to treat multidrug-resistant TB (MDR-TB). BDQ benzoate and maleate have been identified as promising alternatives that will encourage generic pharmaceutical houses to manufacture this drug. Our study compared the phar...

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Detalles Bibliográficos
Autores principales: Jaw-Tsai, S., Barry, R., Pande, P. G., Taneja, R., Yang, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union Against Tuberculosis and Lung Disease 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879086/
https://www.ncbi.nlm.nih.gov/pubmed/36853125
http://dx.doi.org/10.5588/ijtld.22.0326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879086/
https://www.ncbi.nlm.nih.gov/pubmed/36853125
http://dx.doi.org/10.5588/ijtld.22.0326

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