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Comparison of pharmacokinetics and bioavailability of bedaquiline fumarate, benzoate and maleate in dogs
BACKGROUND: Bedaquiline (BDQ) as a fumarate salt is indicated as part of a regimen to treat multidrug-resistant TB (MDR-TB). BDQ benzoate and maleate have been identified as promising alternatives that will encourage generic pharmaceutical houses to manufacture this drug. Our study compared the phar...
Autores principales: | Jaw-Tsai, S., Barry, R., Pande, P. G., Taneja, R., Yang, T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union Against Tuberculosis and Lung Disease
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879086/ https://www.ncbi.nlm.nih.gov/pubmed/36853125 http://dx.doi.org/10.5588/ijtld.22.0326 |
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