New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study

A new series of 2-aminobenzothiazole hybrids linked to thiazolidine-2,4-dione 4a–e, 1,3,4-thiadiazole aryl urea 6a–d, and cyanothiouracil moieties 8a–d was synthesised. The in vitro antitumor effect of the new hybrids was assessed against three cancer cell lines, namely, HCT-116, HEPG-2, and MCF-7 u...

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Detalles Bibliográficos
Autores principales: Al-Sanea, Mohammad M., Hamdi, Abdelrahman, Mohamed, Ahmed A. B., El-Shafey, Hamed W., Moustafa, Mahmoud, Elgazar, Abdullah A., Eldehna, Wagdy M., Ur Rahman, Hidayat, Parambi, Della G. T., Elbargisy, Rehab M., Selim, Samy, Bukhari, Syed Nasir Abbas, Magdy Hendawy, Omnia, Tawfik, Samar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879182/
https://www.ncbi.nlm.nih.gov/pubmed/36691927
http://dx.doi.org/10.1080/14756366.2023.2166036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879182/
https://www.ncbi.nlm.nih.gov/pubmed/36691927
http://dx.doi.org/10.1080/14756366.2023.2166036

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