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Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis

Renal proximal tubular cells are highly vulnerable to different types of assaults during filtration and reabsorption, leading to acute renal dysfunction and eventual chronic kidney diseases (CKD). The chemotherapeutic drug cisplatin elicits cytotoxicity causing renal tubular cell death, but its exec...

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Detalles Bibliográficos
Autores principales: Dong, Xing-Qiang, Chu, Li-Kai, Cao, Xu, Xiong, Qian-Wei, Mao, Yi-Ming, Chen, Ching-Hsien, Bi, Yun-Li, Liu, Jun, Yan, Xiang-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879199/
https://www.ncbi.nlm.nih.gov/pubmed/36692085
http://dx.doi.org/10.1080/13510002.2022.2152607