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Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis
Renal proximal tubular cells are highly vulnerable to different types of assaults during filtration and reabsorption, leading to acute renal dysfunction and eventual chronic kidney diseases (CKD). The chemotherapeutic drug cisplatin elicits cytotoxicity causing renal tubular cell death, but its exec...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879199/ https://www.ncbi.nlm.nih.gov/pubmed/36692085 http://dx.doi.org/10.1080/13510002.2022.2152607 |