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Reduced Number of Thymoma CTLA4-Positive Cells Is Associated With a Higher Probability of Developing Myasthenia Gravis

BACKGROUND AND OBJECTIVES: Myasthenia gravis (MG) is an autoimmune disease associated with comorbid thymoma in 10%–15% of cases. Cytotoxic T lymphocyte–associated antigen 4 (CTLA4) expressed by T cells downregulates T-cell–mediated immune response. Polymorphisms in the CTLA4 gene have been associate...

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Detalles Bibliográficos
Autores principales: Álvarez-Velasco, Rodrigo, Dols-Icardo, Oriol, El Bounasri, Shaima, López-Vilaró, Laura, Trujillo, Juan Carlos, Reyes-Leiva, David, Suárez-Calvet, Xavier, Cortés-Vicente, Elena, Illa, Isabel, Gallardo, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879278/
https://www.ncbi.nlm.nih.gov/pubmed/36697230
http://dx.doi.org/10.1212/NXI.0000000000200085