Oncolytic strategy using new bifunctional HDACs/BRD4 inhibitors against virus-associated lymphomas

Primary effusion lymphoma (PEL) caused by Kaposi sarcoma–associated herpesvirus (KSHV) is an aggressive malignancy with poor prognosis even under chemotherapy. Currently, there is no specific treatment for PEL therefore requiring new therapies. Both histone deacetylases (HDACs) and bromodomain-conta...

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Detalles Bibliográficos
Autores principales: Chen, Jungang, Wang, Zhengyu, Phuc, Tran, Xu, Zhigang, Yang, Donglin, Chen, Zhengzhu, Lin, Zhen, Kendrick, Samantha, Dai, Lu, Li, Hong-yu, Qin, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879403/
https://www.ncbi.nlm.nih.gov/pubmed/36638143
http://dx.doi.org/10.1371/journal.ppat.1011089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879403/
https://www.ncbi.nlm.nih.gov/pubmed/36638143
http://dx.doi.org/10.1371/journal.ppat.1011089

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