Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a(+/)(-) mouse model of Dravet syndrome

A purified preparation of cannabidiol (CBD), a cannabis constituent, has been approved for the treatment of intractable childhood epilepsies such as Dravet syndrome. Extensive pharmacological characterization of CBD shows activity at numerous molecular targets but its anticonvulsant mechanism(s) of...

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Detalles Bibliográficos
Autores principales: Anderson, Lyndsey L., Bahceci, Dilara A., Hawkins, Nicole A., Everett-Morgan, Declan, Banister, Samuel D., Kearney, Jennifer A., Arnold, Jonathon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879440/
https://www.ncbi.nlm.nih.gov/pubmed/36701411
http://dx.doi.org/10.1371/journal.pone.0280842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879440/
https://www.ncbi.nlm.nih.gov/pubmed/36701411
http://dx.doi.org/10.1371/journal.pone.0280842

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