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Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements

Although homologous recombination between transposable elements can drive genomic evolution in yeast by facilitating chromosomal rearrangements, the details of the underlying mechanisms are not fully clarified. In the genome of the yeast Saccharomyces cerevisiae, the most common class of transposon...

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Detalles Bibliográficos
Autores principales: Qi, Lei, Sui, Yang, Tang, Xing-Xing, McGinty, Ryan J., Liang, Xiao-Zhuan, Dominska, Margaret, Zhang, Ke, Mirkin, Sergei M., Zheng, Dao-Qiong, Petes, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879454/
https://www.ncbi.nlm.nih.gov/pubmed/36701275
http://dx.doi.org/10.1371/journal.pgen.1010590