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Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements
Although homologous recombination between transposable elements can drive genomic evolution in yeast by facilitating chromosomal rearrangements, the details of the underlying mechanisms are not fully clarified. In the genome of the yeast Saccharomyces cerevisiae, the most common class of transposon...
Autores principales: | Qi, Lei, Sui, Yang, Tang, Xing-Xing, McGinty, Ryan J., Liang, Xiao-Zhuan, Dominska, Margaret, Zhang, Ke, Mirkin, Sergei M., Zheng, Dao-Qiong, Petes, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879454/ https://www.ncbi.nlm.nih.gov/pubmed/36701275 http://dx.doi.org/10.1371/journal.pgen.1010590 |
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