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Conformational dynamics and putative substrate extrusion pathways of the N-glycosylated outer membrane factor CmeC from Campylobacter jejuni

The outer membrane factor CmeC of the efflux machinery CmeABC plays an important role in conferring antibiotic and bile resistance to Campylobacter jejuni. Curiously, the protein is N-glycosylated, with the glycans playing a key role in the effective function of this system. In this work we have emp...

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Detalles Bibliográficos
Autores principales: Newman, Kahlan E., Khalid, Syma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879487/
https://www.ncbi.nlm.nih.gov/pubmed/36638139
http://dx.doi.org/10.1371/journal.pcbi.1010841