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Case report: Identification of a novel HNRNPC::RARG fusion in acute promyelocytic leukemia lacking RARA rearrangement

Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia (AML), 95% patients have PML-RARA fusion gene as a result of a reciprocal chromosomal translocation t(15;17)(q22; q21). The retinoic acid receptors (RARs) belong to nuclear hormone receptors which modulate the transcri...

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Detalles Bibliográficos
Autores principales: Ding, Wenjing, Weng, Guangyang, Wang, Zheng, Guo, Yusha, Wang, Man, Shen, Hongjie, Chen, Suning, Du, Xin, Wen, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879720/
https://www.ncbi.nlm.nih.gov/pubmed/36713535
http://dx.doi.org/10.3389/fonc.2022.1028651