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A unified mediation analysis framework for integrative cancer proteogenomics with clinical outcomes

MOTIVATION: Multilevel molecular profiling of tumors and the integrative analysis with clinical outcomes have enabled a deeper characterization of cancer treatment. Mediation analysis has emerged as a promising statistical tool to identify and quantify the intermediate mechanisms by which a gene aff...

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Detalles Bibliográficos
Autores principales: Huang, Licai, Long, James P, Irajizad, Ehsan, Doecke, James D, Do, Kim-Anh, Ha, Min Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879726/
https://www.ncbi.nlm.nih.gov/pubmed/36648331
http://dx.doi.org/10.1093/bioinformatics/btad023