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A unified mediation analysis framework for integrative cancer proteogenomics with clinical outcomes
MOTIVATION: Multilevel molecular profiling of tumors and the integrative analysis with clinical outcomes have enabled a deeper characterization of cancer treatment. Mediation analysis has emerged as a promising statistical tool to identify and quantify the intermediate mechanisms by which a gene aff...
Autores principales: | Huang, Licai, Long, James P, Irajizad, Ehsan, Doecke, James D, Do, Kim-Anh, Ha, Min Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879726/ https://www.ncbi.nlm.nih.gov/pubmed/36648331 http://dx.doi.org/10.1093/bioinformatics/btad023 |
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