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Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation

A high-salt diet significantly impacts various diseases, ilncluding cancer and immune diseases. Recent studies suggest that the high-salt/hyperosmotic environment in the body may alter the chronic properties of cancer and immune cells in the disease context. However, little is known about the acute...

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Detalles Bibliográficos
Autores principales:	Ikizawa, Takeshi, Ikeda, Kazutaka, Arita, Makoto, Kitajima, Shojiro, Soga, Tomoyoshi, Ichijo, Hidenori, Naguro, Isao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879793/ https://www.ncbi.nlm.nih.gov/pubmed/36581206 http://dx.doi.org/10.1016/j.jbc.2022.102837

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