Effect of pharmacogenetic variations on praziquantel plasma concentration and safety outcomes among school children in Rwanda

School-based mass drug administration (MDA) of Praziquantel (PZQ) is the global intervention strategy for elimination of schistosomiasis. Genetic variations in drug metabolizing enzymes and transporter proteins influences drug exposure and treatment outcomes, but data on PZQ pharmacokinetics and saf...

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Detalles Bibliográficos
Autores principales: Barry, Abbie, Kabatende, Joseph, Telele, Nigus Fikrie, Mnkugwe, Rajabu Hussein, Mugisha, Michael, Ntirenganya, Lazare, Bienvenu, Emile, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879930/
https://www.ncbi.nlm.nih.gov/pubmed/36702944
http://dx.doi.org/10.1038/s41598-023-28641-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879930/
https://www.ncbi.nlm.nih.gov/pubmed/36702944
http://dx.doi.org/10.1038/s41598-023-28641-w

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