Regions of hepatitis C virus E2 required for membrane association

Hepatitis C virus (HCV) uses a hybrid entry mechanism. Current structural data suggest that upon exposure to low pH and Cluster of Differentiation 81 (CD81), the amino terminus of envelope glycoprotein E2 becomes ordered and releases an internal loop with two invariant aromatic residues into the hos...

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Detalles Bibliográficos
Autores principales: Kumar, Ashish, Rohe, Tiana C., Elrod, Elizabeth J., Khan, Abdul G., Dearborn, Altaira D., Kissinger, Ryan, Grakoui, Arash, Marcotrigiano, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879980/
https://www.ncbi.nlm.nih.gov/pubmed/36702826
http://dx.doi.org/10.1038/s41467-023-36183-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879980/
https://www.ncbi.nlm.nih.gov/pubmed/36702826
http://dx.doi.org/10.1038/s41467-023-36183-y

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