TadA reprogramming to generate potent miniature base editors with high precision

Although miniature CRISPR-Cas12f systems were recently developed, the editing efficacy and targeting range of derived miniature cytosine and adenine base editors (miniCBEs and miniABEs) have not been comprehensively addressed. Moreover, functional miniCBEs have not yet be established. Here we genera...

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Detalles Bibliográficos
Autores principales: Zhang, Shuqian, Song, Liting, Yuan, Bo, Zhang, Cheng, Cao, Jixin, Chen, Jinlong, Qiu, Jiayi, Tai, Yilin, Chen, Jingqi, Qiu, Zilong, Zhao, Xing-Ming, Cheng, Tian-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879996/
https://www.ncbi.nlm.nih.gov/pubmed/36702845
http://dx.doi.org/10.1038/s41467-023-36004-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879996/
https://www.ncbi.nlm.nih.gov/pubmed/36702845
http://dx.doi.org/10.1038/s41467-023-36004-2

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