TadA orthologs enable both cytosine and adenine editing of base editors

Cytidine and adenosine deaminases are required for cytosine and adenine editing of base editors respectively, and no single deaminase could enable concurrent and comparable cytosine and adenine editing. Additionally, distinct properties of cytidine and adenosine deaminases lead to various types of o...

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Detalles Bibliográficos
Autores principales: Zhang, Shuqian, Yuan, Bo, Cao, Jixin, Song, Liting, Chen, Jinlong, Qiu, Jiayi, Qiu, Zilong, Zhao, Xing-Ming, Chen, Jingqi, Cheng, Tian-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880001/
https://www.ncbi.nlm.nih.gov/pubmed/36702837
http://dx.doi.org/10.1038/s41467-023-36003-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880001/
https://www.ncbi.nlm.nih.gov/pubmed/36702837
http://dx.doi.org/10.1038/s41467-023-36003-3

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