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Reprogramming systemic and local immune function to empower immunotherapy against glioblastoma

The limited benefits of immunotherapy against glioblastoma (GBM) is closely related to the paucity of T cells in brain tumor bed. Both systemic and local immunosuppression contribute to the deficiency of tumor-infiltrating T cells. However, the current studies focus heavily on the local immunosuppre...

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Detalles Bibliográficos
Autores principales: Zhou, Songlei, Huang, Yukun, Chen, Yu, Liu, Yipu, Xie, Laozhi, You, Yang, Tong, Shiqiang, Xu, Jianpei, Jiang, Gan, Song, Qingxiang, Mei, Ni, Ma, Fenfen, Gao, Xiaoling, Chen, Hongzhuan, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880004/
https://www.ncbi.nlm.nih.gov/pubmed/36702831
http://dx.doi.org/10.1038/s41467-023-35957-8