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Comprehensive genome-scale metabolic model of the human pathogen Cryptococcus neoformans: A platform for understanding pathogen metabolism and identifying new drug targets

Introduction: The fungal priority pathogen Cryptococcus neoformans causes cryptococcal meningoencephalitis in immunocompromised individuals and leads to hundreds of thousands of deaths per year. The undesirable side effects of existing treatments, the need for long application times to prevent the d...

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Detalles Bibliográficos
Autores principales: Tezcan, Enes Fahri, Demirtas, Yigit, Cakar, Zeynep Petek, Ulgen, Kutlu O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880062/
https://www.ncbi.nlm.nih.gov/pubmed/36714093
http://dx.doi.org/10.3389/fbinf.2023.1121409