Effects of down-regulation of ackA expression by CRISPR-dCpf1 on succinic acid production in Actinobacillus succinogenes

Succinic acid (SA), a key intermediate in the cellular tricarboxylic acid cycle (TCA), is a 4-carbon dicarboxylic acid of great industrial value. Actinobacillus succinogenes can ferment various carbon sources and accumulate relatively high concentrations of SA, but few reliable genetic engineering t...

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Detalles Bibliográficos
Autores principales: Chen, Chunmei, Zheng, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880102/
https://www.ncbi.nlm.nih.gov/pubmed/36700989
http://dx.doi.org/10.1186/s13568-023-01518-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880102/
https://www.ncbi.nlm.nih.gov/pubmed/36700989
http://dx.doi.org/10.1186/s13568-023-01518-x

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