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Growth differentiation factor 10 induces angiogenesis to promote wound healing in rats with diabetic foot ulcers by activating TGF-β1/Smad3 signaling pathway

BACKGROUND: Diabetic foot ulcer (DFU) represents a highly-prevalent complication of diabetes mellitus (DM). Herein, the current study sought to identify the role of growth differentiation factor 10 (GDF-10) in wound healing in DFU via regulation of the transforming growth factor-beta 1 (TGF-β1)/Smad...

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Detalles Bibliográficos
Autores principales: Zhao, Qingsong, Xu, Jinmei, Han, Xu, Zhang, Zheqi, Qu, Jiahui, Cheng, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880151/
https://www.ncbi.nlm.nih.gov/pubmed/36714584
http://dx.doi.org/10.3389/fendo.2022.1013018