Methylation status of hypothalamic Mkrn3 promoter across puberty

Makorin RING finger protein 3 (MKRN3) is an important factor located on chromosome 15 in the imprinting region associated with Prader-Willi syndrome. Imprinted MKRN3 is expressed in hypothalamic regions essential for the onset of puberty and mutations in the gene have been found in patients with cen...

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Detalles Bibliográficos
Autores principales: Fanis, Pavlos, Morrou, Maria, Tomazou, Marios, Michailidou, Kyriaki, Spyrou, George M., Toumba, Meropi, Skordis, Nicos, Neocleous, Vassos, Phylactou, Leonidas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880154/
https://www.ncbi.nlm.nih.gov/pubmed/36714607
http://dx.doi.org/10.3389/fendo.2022.1075341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880154/
https://www.ncbi.nlm.nih.gov/pubmed/36714607
http://dx.doi.org/10.3389/fendo.2022.1075341

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