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Heterodimeric IL-15 (hetIL-15) reduces circulating tumor cells and metastasis formation improving chemotherapy and surgery in 4T1 mouse model of TNBC

Immunotherapy has emerged as a viable approach in cancer therapy, with cytokines being of great interest. Interleukin IL-15 (IL-15), a cytokine that supports cytotoxic immune cells, has been successfully tested as an anti-cancer and anti-metastatic agent, but combinations with conventional chemother...

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Detalles Bibliográficos
Autores principales: Stravokefalou, Vasiliki, Stellas, Dimitris, Karaliota, Sevasti, Nagy, Bethany A., Valentin, Antonio, Bergamaschi, Cristina, Dimas, Konstantinos, Pavlakis, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880212/
https://www.ncbi.nlm.nih.gov/pubmed/36713398
http://dx.doi.org/10.3389/fimmu.2022.1014802