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Knocking out central metabolism genes to identify new targets and alternating substrates to improve lipid synthesis in Y. lipolytica

Introduction: Systematic gene knockout studies may offer us novel insights on cell metabolism and physiology. Specifically, the lipid accumulation mechanism at the molecular or cellular level is yet to be determined in the oleaginous yeast Y. lipolytica. Methods: Herein, we established ten engineere...

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Detalles Bibliográficos
Autores principales: Zhu, Jiang, Gu, Yang, Yan, Yijing, Ma, Jingbo, Sun, Xiaoman, Xu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880266/
https://www.ncbi.nlm.nih.gov/pubmed/36714010
http://dx.doi.org/10.3389/fbioe.2023.1098116