Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling

INTRODUCTION: The development of reliable hepatic in vitro models may provide insights into disease mechanisms, linking hepatocyte dysmetabolism and related pathologies. However, several of the existing models depend on using high concentrations of hepatocyte differentiation-promoting compounds, nam...

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Detalles Bibliográficos
Autores principales: Rodrigues, Joana Saraiva, Faria-Pereira, Andreia, Camões, Sérgio Póvoas, Serras, Ana Sofia, Morais, Vanessa Alexandra, Ruas, Jorge Lira, Miranda, Joana Paiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880320/
https://www.ncbi.nlm.nih.gov/pubmed/36714559
http://dx.doi.org/10.3389/fendo.2022.1043543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880320/
https://www.ncbi.nlm.nih.gov/pubmed/36714559
http://dx.doi.org/10.3389/fendo.2022.1043543

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