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Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling
INTRODUCTION: The development of reliable hepatic in vitro models may provide insights into disease mechanisms, linking hepatocyte dysmetabolism and related pathologies. However, several of the existing models depend on using high concentrations of hepatocyte differentiation-promoting compounds, nam...
Autores principales: | Rodrigues, Joana Saraiva, Faria-Pereira, Andreia, Camões, Sérgio Póvoas, Serras, Ana Sofia, Morais, Vanessa Alexandra, Ruas, Jorge Lira, Miranda, Joana Paiva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880320/ https://www.ncbi.nlm.nih.gov/pubmed/36714559 http://dx.doi.org/10.3389/fendo.2022.1043543 |
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