SL-Cloud: A Cloud-based resource to support synthetic lethal interaction discovery

Synthetic lethal interactions (SLIs), genetic interactions in which the simultaneous inactivation of two genes leads to a lethal phenotype, are promising targets for therapeutic intervention in cancer, as exemplified by the recent success of PARP inhibitors in treating BRCA1/2-deficient tumors. We p...

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Detalles Bibliográficos
Autores principales: Tercan, Bahar, Qin, Guangrong, Kim, Taek-Kyun, Aguilar, Boris, Phan, John, Longabaugh, William, Pot, David, Kemp, Christopher J., Chambwe, Nyasha, Shmulevich, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Software Tool Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880341/
https://www.ncbi.nlm.nih.gov/pubmed/36761837
http://dx.doi.org/10.12688/f1000research.110903.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880341/
https://www.ncbi.nlm.nih.gov/pubmed/36761837
http://dx.doi.org/10.12688/f1000research.110903.2

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