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Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage

Introduction: Huntington disease is an autosomal dominant neurodegenerative disorder which is caused by a CAG repeat expansion in the HTT gene that codes for an elongated polyglutamine tract in the huntingtin (HTT) protein. Huntingtin is subjected to multiple post-translational modifications which r...

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Detalles Bibliográficos
Autores principales:	Lemarié, Fanny L., Sanders, Shaun S., Nguyen, Yen, Martin, Dale D. O., Hayden, Michael R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880554/ https://www.ncbi.nlm.nih.gov/pubmed/36711022 http://dx.doi.org/10.3389/fphys.2023.1086112

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