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Sequential Polyadenylation to Enable Alternative mRNA 3’ End Formation

In eukaryotic cells, a key RNA processing step to generate mature mRNA is the coupled reaction for cleavage and polyadenylation (CPA) at the 3′ end of individual transcripts. Many transcripts are alternatively polyadenylated (APA) to produce mRNAs with different 3′ ends that may either alter protein...

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Detalles Bibliográficos
Autores principales: Hao, Yajing, Cai, Ting, Liu, Chang, Zhang, Xuan, Fu, Xiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880608/
https://www.ncbi.nlm.nih.gov/pubmed/36697238
http://dx.doi.org/10.14348/molcells.2023.2176