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CYP1A2 Genetic Variation, Coffee Intake, and Kidney Dysfunction

IMPORTANCE: Caffeine is detoxified by cytochrome P450 1A2 (CYP1A2), and genetic variation in CYP1A2 impacts the rate of caffeine clearance. Factors that may modify the association between coffee intake and kidney disease remain unclear. OBJECTIVE: To assess whether CYP1A2 genotype modifies the assoc...

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Detalles Bibliográficos
Autores principales: Mahdavi, Sara, Palatini, Paolo, El-Sohemy, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880799/
https://www.ncbi.nlm.nih.gov/pubmed/36701157
http://dx.doi.org/10.1001/jamanetworkopen.2022.47868