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CYP1A2 Genetic Variation, Coffee Intake, and Kidney Dysfunction
IMPORTANCE: Caffeine is detoxified by cytochrome P450 1A2 (CYP1A2), and genetic variation in CYP1A2 impacts the rate of caffeine clearance. Factors that may modify the association between coffee intake and kidney disease remain unclear. OBJECTIVE: To assess whether CYP1A2 genotype modifies the assoc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9880799/ https://www.ncbi.nlm.nih.gov/pubmed/36701157 http://dx.doi.org/10.1001/jamanetworkopen.2022.47868 |