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Subtle Differences in Cognition in 70-Year-Olds with Elevated Cerebrospinal Fluid Neurofilament Light and Neurogranin: A H70 Cross-Sectional Study

BACKGROUND: Most research on cerebrospinal fluid (CSF) neurofilament light protein (NfL) as a marker for neurodegeneration and neurogranin (Ng) for synaptic dysfunction has largely focused on clinical cohorts rather than population-based samples. OBJECTIVE: We hypothesized that increased CSF levels...

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Detalles Bibliográficos
Autores principales: Rådestig, Maya Arvidsson, Skoog, Johan, Zetterberg, Henrik, Skillbäck, Tobias, Zettergren, Anna, Sterner, Therese Rydberg, Fässberg, Madeleine Mellqvist, Sacuiu, Simona, Waern, Margda, Wetterberg, Hanna, Blennow, Kaj, Skoog, Ingmar, Kern, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881027/
https://www.ncbi.nlm.nih.gov/pubmed/36617786
http://dx.doi.org/10.3233/JAD-220452