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Concordance of Alzheimer’s Disease-Related Biomarkers Between Intraventricular and Lumbar Cerebrospinal Fluid in Idiopathic Normal Pressure Hydrocephalus

BACKGROUND: Alzheimer’s disease cerebrospinal fluid (CSF) biomarkers amyloid-β 1–42 (Aβ(42)), total tau (T-tau), and phosphorylated tau 181 (P-tau(181)) are widely used. However, concentration gradient of these biomarkers between intraventricular (V-CSF) and lumbar CSF (L-CSF) has been demonstrated...

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Detalles Bibliográficos
Autores principales: Lukkarinen, Heikki, Vanninen, Aleksi, Tesseur, Ina, Pemberton, Darrel, Van Der Ark, Peter, Kokkola, Tarja, Herukka, Sanna-Kaisa, Rauramaa, Tuomas, Hiltunen, Mikko, Blennow, Kaj, Zetterberg, Henrik, Leinonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881032/
https://www.ncbi.nlm.nih.gov/pubmed/36404546
http://dx.doi.org/10.3233/JAD-220652