The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

The lysine acetyltransferase KAT6A (MOZ, MYST3) belongs to the MYST family of chromatin regulators, facilitating histone acetylation. Dysregulation of KAT6A has been implicated in developmental syndromes and the onset of acute myeloid leukemia (AML). Previous work suggests that KAT6A is recruited to...

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Detalles Bibliográficos
Autores principales: Weber, Lisa Marie, Jia, Yulin, Stielow, Bastian, Gisselbrecht, Stephen S, Cao, Yinghua, Ren, Yanpeng, Rohner, Iris, King, Jessica, Rothman, Elisabeth, Fischer, Sabrina, Simon, Clara, Forné, Ignasi, Nist, Andrea, Stiewe, Thorsten, Bulyk, Martha L, Wang, Zhanxin, Liefke, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881136/
https://www.ncbi.nlm.nih.gov/pubmed/36537216
http://dx.doi.org/10.1093/nar/gkac1188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881136/
https://www.ncbi.nlm.nih.gov/pubmed/36537216
http://dx.doi.org/10.1093/nar/gkac1188

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