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POT-3 preferentially binds the terminal DNA-repeat on the telomeric G-overhang

Eukaryotic chromosomes typically end in 3′ telomeric overhangs. The safeguarding of telomeric single-stranded DNA overhangs is carried out by factors related to the protection of telomeres 1 (POT1) protein in humans. Of the three POT1-like proteins in Caenorhabditis elegans, POT-3 was the only membe...

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Detalles Bibliográficos
Autores principales: Yu, Xupeng, Gray, Sean, Ferreira, Helder C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881156/
https://www.ncbi.nlm.nih.gov/pubmed/36583365
http://dx.doi.org/10.1093/nar/gkac1203