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Total Synthesis of (−)-Cylindricine H

[Image: see text] Starting from (R)-phenylglycinol-derived tricyclic lactam 1, the enantioselective synthesis of (−)-cylindricine H is reported. From the stereochemical standpoint, the key steps are the stereoselective generation of the quaternary C(10) stereocenter, the stereoselective introduction...

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Detalles Bibliográficos
Autores principales: Piccichè, Miriam, Pinto, Alexandre, Griera, Rosa, Bosch, Joan, Amat, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881165/
https://www.ncbi.nlm.nih.gov/pubmed/35849750
http://dx.doi.org/10.1021/acs.orglett.2c02004