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Biomimetic Synthesis of Chejuenolides A–C by a Cryptic Lactone-Based Macrocyclization: Stereochemical Implications in Biosynthesis
[Image: see text] A hypothetical Mannich macrocyclization in the biosynthesis of chejuenolides A–C served as the basis for the synthetic design herein. Using a lactone-based linear precursor constructed via a tactic sequence of aldol–Julia–aldol reactions on a gram scale, the biomimetic total synthe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881209/ https://www.ncbi.nlm.nih.gov/pubmed/36712486 http://dx.doi.org/10.1021/acscentsci.2c01096 |