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Safety and efficacy of trifluridine/tipiracil in previously treated metastatic colorectal cancer: final results from the phase IIIb single-arm PRECONNECT study by duration of therapy

BACKGROUND: PRECONNECT was an international, phase IIIb trial evaluating the safety and efficacy of trifluridine/tipiracil (FTD/TPI) for metastatic colorectal cancer (mCRC). METHODS: Patients with mCRC received FTD/TPI 35 mg/m(2) twice-daily on days 1–5 and 8–12 of each 28-day cycle for third- or la...

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Detalles Bibliográficos
Autores principales: Taieb, Julien, Price, Timothy, Vidot, Loïck, Chevallier, Bénédicte, Wyrwicz, Lucjan, Bachet, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881327/
https://www.ncbi.nlm.nih.gov/pubmed/36707808
http://dx.doi.org/10.1186/s12885-022-10489-4