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Circ VRK1/microRNA-17/PTEN axis modulates the angiogenesis of human brain microvascular endothelial cells to affect injury induced by oxygen-glucose deprivation/reperfusion

BACKGROUND: Circular RNAs (circRNAs) can act as microRNA (miRNA) sponges, thus regulating gene expression. The role of circRNAs in the process of oxygen-glucose deprivation/reoxygenation (OGD/R) is unclear. Here, we explored the mechanism underlying Circ VRK1 in human brain microvascular endothelial...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Du, Hong, Zhang, Xuejing, Gao, Bulang, Zhang, Dongliang, Qiao, Zongrong, Su, Xianhui, Bao, Tong, Han, Siqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881374/
https://www.ncbi.nlm.nih.gov/pubmed/36707796
http://dx.doi.org/10.1186/s12868-023-00774-8