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Hybrid peptide NTP-217 triggers ROS-mediated rapid necrosis in liver cancer cells by induction of mitochondrial leakage

Liver cancer is the third leading cause of cancer-associated mortality globally, and >830,000 patients with liver cancer undergoing treatment succumbed to the disease in 2020, which indicates the urgent need to develop a more effective anti-liver cancer drug. In our previous study, nucleus-target...

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Detalles Bibliográficos
Autores principales: Yin, Hao, Fu, Xingyan, Gao, Hanyu, Gao, Han, Ma, Yannan, Chen, Xitong, Zhang, Xueqi, Du, Shan-Shan, Qi, Yun-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881410/
https://www.ncbi.nlm.nih.gov/pubmed/36713538
http://dx.doi.org/10.3389/fonc.2022.1028600