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Paternal morphine exposure enhances morphine self-administration and induces region-specific neural adaptations in reward-related brain regions of male offspring

BACKGROUND: A growing body of preclinical studies report that preconceptional experiences can have a profound and long-lasting impact on adult offspring behavior and physiology. However, less is known about paternal drug exposure and its effects on reward sensitivity in the next generation. METHODS:...

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Detalles Bibliográficos
Autores principales: Toussaint, Andre B., Ellis, Alexandra S., Bongiovanni, Angela R., Peterson, Drew R., Bavley, Charlotte C., Karbalaei, Reza, Mayberry, Hannah L., Bhakta, Shivam, Dressler, Carmen C., Imperio, Caesar G., Maurer, John J., Schmidt, Heath D., Chen, Chongguang, Bland, Kathryn, Liu-Chen, Lee-Yuan, Wimmer, Mathieu E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881847/
https://www.ncbi.nlm.nih.gov/pubmed/36711571
http://dx.doi.org/10.1101/2023.01.03.522600