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Pore-like diffusion barriers in murine cardiac myocytes

Using both optical and electrical methods, we document that solute diffusion in the cytoplasm of BL6 murine cardiac myocytes becomes restricted >30-fold as molecular weight increases from 30 to 2000, roughly as expected for pores with dimensions of cardiac porin channels. The Bodipy-FL ATP analog...

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Detalles Bibliográficos
Autores principales: Deisl, Christine, Chung, Jay A., Hilgemann, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881867/
https://www.ncbi.nlm.nih.gov/pubmed/36712045
http://dx.doi.org/10.1101/2023.01.02.522313