MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

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The molecular circadian clock, which controls rhythmic 24-hour oscillation of genes, proteins, and metabolites in healthy tissues, is disrupted across many human cancers. Deregulated expression of the MYC oncoprotein has been shown to alter expression of molecular clock genes, leading to a disruptio...

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Detalles Bibliográficos
Autores principales: Cazarin, Juliana, DeRollo, Rachel E., Ahmad Shahidan, Siti Noor Ain Binti, Burchett, Jamison B., Mwangi, Daniel, Krishnaiah, Saikumari, Hsieh, Annie L., Walton, Zandra E., Brooks, Rebekah, Mello, Stephano S., Weljie, Aalim M., Dang, Chi V., Altman, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881876/
https://www.ncbi.nlm.nih.gov/pubmed/36711638
http://dx.doi.org/10.1101/2023.01.03.522637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881876/
https://www.ncbi.nlm.nih.gov/pubmed/36711638
http://dx.doi.org/10.1101/2023.01.03.522637

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