Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis during long bone growth

Skeletal development depends on coordinated angiogenesis and osteogenesis. Bone morphogenetic proteins direct bone development by activating SMAD1/5 signaling in osteoblasts. However, the role of SMAD1/5 in skeletal endothelium is unknown. Here, we found that endothelial cell-conditional SMAD1/5 dep...

Descripción completa

Detalles Bibliográficos
Autores principales: Lang, Annemarie, Benn, Andreas, Wolter, Angelique, Balcaen, Tim, Collins, Joseph, Kerckhofs, Greet, Zwijsen, An, Boerckel, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881901/
https://www.ncbi.nlm.nih.gov/pubmed/36712097
http://dx.doi.org/10.1101/2023.01.07.522994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881901/
https://www.ncbi.nlm.nih.gov/pubmed/36712097
http://dx.doi.org/10.1101/2023.01.07.522994

Ejemplares similares