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Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis during long bone growth

Skeletal development depends on coordinated angiogenesis and osteogenesis. Bone morphogenetic proteins direct bone development by activating SMAD1/5 signaling in osteoblasts. However, the role of SMAD1/5 in skeletal endothelium is unknown. Here, we found that endothelial cell-conditional SMAD1/5 dep...

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Detalles Bibliográficos
Autores principales:	Lang, Annemarie, Benn, Andreas, Wolter, Angelique, Balcaen, Tim, Collins, Joseph, Kerckhofs, Greet, Zwijsen, An, Boerckel, Joel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881901/ https://www.ncbi.nlm.nih.gov/pubmed/36712097 http://dx.doi.org/10.1101/2023.01.07.522994

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