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Sequential unfolding mechanisms of monomeric caspases
Caspases are evolutionarily conserved cysteinyl proteases that are integral in cell development and apoptosis. All apoptotic caspases evolved from a common ancestor into two distinct subfamilies with either monomeric (initiators) or dimeric (effectors) oligomeric states. The regulation of apoptosis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881926/ https://www.ncbi.nlm.nih.gov/pubmed/36711547 http://dx.doi.org/10.1101/2023.01.04.522771 |