Dock7 regulates AKT and mTOR/S6K activity required for the transformed phenotypes and survival of cancer cells

Cancer cells, both within a developing tumor and during metastatic spread, encounter many stresses that require adaptive mechanisms to survive and maintain malignant progression. Here we describe a signaling complex involving the small GTPase Cdc42 and Dock7, a Cdc42/Rac GEF and unique Cdc42-effecto...

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Detalles Bibliográficos
Autores principales: Teran, Oriana Y., Zanotelli, Matthew R., Lin, Miao-chong Joy, Cerione, Richard A., Wilson, Kristin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881951/
https://www.ncbi.nlm.nih.gov/pubmed/36711811
http://dx.doi.org/10.1101/2023.01.03.522657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881951/
https://www.ncbi.nlm.nih.gov/pubmed/36711811
http://dx.doi.org/10.1101/2023.01.03.522657

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